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Congenital Heart Disease/Thyroid Disease Connection

By , About.com Guide

Created: December 13, 2003

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The linkage between thyroid disease and heart disease is established. Undiagnosed, untreated or undertreated hypothyroidism -- a condition of insufficient thyroid hormone -- can increase cholesterol levels and increases the risk of heart disease in adults. Hyperthyroidism -- a condition of an excess of thyroid hormone -- can also increase the risk of heart attacks, due to increased blood pressure, rapid heartbeat, and in some cases, palpitations and atrial fibrillation.

When it comes to infants and children, there are also some important thyroid disease/heart disease links to be aware of:
  • Iodine Exposure -- Exposure to iodine, such as might occur during cardiac catheterisation or surgery, may induce a transient form of hypothyroidism in infants.
  • Amiodarone/Heart Drug -- The heart drug amiodarone, which is an extremely effective treatment for infants and children with tachyarrhythmias that resist conventional treatment, may also cause hypothyroidism as a side effect.
  • Neonatal Hyperthyroidism -- When a mother is hyperthyroid, thyroid stimulating immunoglobulin can cross the placental barrier and stimulate the fetal thyroid gland, causing neonatal hyperthyroidism. This condition can cause tachycardia, bounding pulses, systolic hypertension, a precordial systolic murmur, and sometimes congestive heart failure, in infants. Other common symptoms are poor weight gain, nervousness or irritability, and prominent eyes.
  • Delayed Treatment for Neonatal Hyperthyroidism -- If treatment for neonatal hyperthyroidism is delayed or inadequate, potentially fatal arrhythmias and cardiac failure may develop.
  • Congenital Cardiac Anomalies -- These anomalies are more common in infants with congenital hypothyroidism than in the average population
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