Oct 20 2003
REFERENCES:1. Walsh JP, et al. "Combined Thyroxine/Liothyronine Treatment Does Not Improve Well-Being, Quality of Life, or Cognitive Function Compared to Thyroxine Alone: A Randomized Controlled Trial in Patients with Primary Hypothyroidism." 2003; JCEM 88(10): 4543-50.
2. Sawka AM, Gerstein HC, et al. "Does a Combination Regimen of Thyroxine (T4) and 3,5,3'-Triiodothyronine Improve Depressive Symptoms Better Than T4 Alone in Patients with Hypothyroidism? Results of a Double-Blind, Randomized, Controlled Trial.” 2003; JCEM 88(10): 4551-55.
3. Kaplan MM, et al. “Editorial: In Search of the Impossible Dream? Thyroid Hormone Replacement Therapy That Treats All Symptoms in All Hypothyroid Patients.” 2003; JCEM 88(10): 4540-2.
4. Bunevicius R, et al. “Effects of thyroxine as compared with thyroxine plus triiodothyronine in patients with hypothyroidism.” NEJM 1999; 340: 424-9.
5. Bunevicius R, et al. “Mental improvement after replacement teherapy with thyroxine plus triiodothyronine: relationship to cause of hypothyroidism.” Int J Neuropsychopharmacol 2000; 3: 167-174.
6. Baskin HJ, et al. “American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Evaluation and Treatment of Hyperthyroidism and Hypothyroidism.” Endocrine Practice 2002; 8(6): 457-469.
7. McDermontt MT, Ridgway EC. “Subclinical hypothyroidism is mild thyroid failure and should be treated.” JCEM 2001; 86: 4585-90.
8. Chu JW, Crapo LM. “The treatment of subclinical hypothyroidism is seldom necessary.” JCEM 2001; 86: 4591-99.
9. Wren JC. “Symptomatic atherosclerosis: prevention or modification by treatment with dessicated thyroid.” J Am Geriatr Soc 1971; 19: 7-22.
10. Franklin JA, et al. “Long-term thyroxine treatment and bone mineral density.” Lancet 1992; 340: 9-13.
11. Gaby AR. “Treatment with thyroid hormone.” JAMA 1989; 262: 1774.
12. Maenpaa J, Liewendah K. “Peripheral insensitivity to thyroid hormones in a euthyroid girl with goiter.” Arch Dis Child 1980; 55: 207.
13. Woliner, KW. “Understanding Thyroid Lab Tests.” 2002; Published on-line at http://www.thyroid-info.com/articles/woliner.htm
14 Pope VJ. “Are autoimmune thyroid dysfunction and depression related?” JCEM 1998; 83(9): 3194-7.
15. Brent GA. “The molecular basis of thyroid hormone action. NEJM 1994; 331: 847-853.
16. Gartner R. “Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations. JCEM 2002; 87(4): 1687-91.
17. Goodwin JS. “The tomato effect. Rejection of highly efficacious therapies.” JAMA 1984; 251(18): 2387-90.
18. Vanderpump MPJ, Tunbridge WMG, French JM, et al. The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham survey. Clin Endocrinol (Oxf) 1995; 43:55–68.
19. Canaris GJ, Manowitz NR, Mayor G, et al. The Colorado thyroid disease prevalence study. Arch Intern Med 2000; 160:526–534.
20. “Drug-company influence on medical education in USA” Lancet 2000; 356(9232): 781.
Reprinted by permission. This article originally published online.
