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What are Goitrogens and How Do they Affect the Thyroid?

By Mary Shomon, About.com

About.com Health's Disease and Condition content is reviewed by our Medical Review Board

Question: What are Goitrogens and How Do they Affect the Thyroid?

Answer: Goitrogenic foods like brussels sprouts, rutabaga, turnips, cauliflower, African cassava, millet, babassu (a palm-tree coconut fruit popular in Brazil and Africa) cabbage, and kale can act like the antithyroid drugs propylthiouracil and methimazole in disabling the thyroid function, so they should not be eaten in large amounts by someone on thyroid hormone replacement who still has a thyroid. It's thought that the enzymes involved in the formation of goitrogenic materials in plants can be destroyed by cooking, so thorough cooking may minimize goitrogenic potential.

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